Researchers from University of California, suggest that higher levels of vitamin D are associated with decreasing risk of breast cancer.
According to researchers, the human blood should contain 60 nanogram per millimeter of 25(OH)D, which is a major variant of vitamin D in blood.
The researchers from University of California analyzed the relation of breast cancer with serum 25-hydroxyvitamin D (25(OH)D) concentrations. The data collected between 2002 and 2017, consisted of around 3,000 participants. The average age of the participant was 63 and all were above 55. None of them had cancer when enrolled. However, 77 cases of breast cancer emerged over a period of four years.
The relation between 25(OH)D and breast cancer was quantified by using Multivariate regression. The results were adjusted for age, BMI, cigarette smoking and intake of calcium supplements and reveled that higher levels of vitamin D in blood could decrease the risk of breast cancer. The participants with less than 20ng/ml of 25(OH)D were more prone to breast cancer than those with 60 ng/ml in their blood. Previous studies by researchers have proved that Vitamin D and calcium together reduced the risk of colon cancer, lung and bladder cancers, multiple myeloma and adult leukemia. The study was published online on Public Library of Science (PLOS) One on June 15, 2018.
Dietary supplements of 4,000 to 6,000 international units (IU) per day and a moderate exposure to sunlight with very minimal clothing is required to achieve 60ng/ml of 25(OH)D. 400 IU of Vitamin D3 every day is regulated in children. The amount is 600 IU for ages one to 70 and 800 for those over 70 years of age. The study was majorly focused on postmenopausal breast cancer. However, further study is required to establish relation between vitamin D and premenopausal breast cancer.